168. Krey L.C., Padmanabhan V., Beitins I.Z. Progesterone modulation of gonadotropin secretion by dispersed rat pituitary cells in culture follicle stimulating hormone synthesis and release // Mol. Cell. Endocrinol. – 1993. – 91, N 1 2. – P. 13-20.
169. Krieger D.T. Brain peptides: what, where and why? // Science. – 1983. – 222, N 4627. – P. 975-985.
170. Lacourse K.A., Friishansen L., Rehfeld J.F., Samuelson L.C. Disturbed progastrin processing in carboxypeptidase E deficient fat mice // FEBS Lett. – 1997. – 416, N 1. – P. 45-50.
171. Lancel M., Faulhaber J., Holsboer F., Rupprecht R. The GABA (A) receptor antagonist picrotoxin attenuates most sleep changes induced by progesterone. // Psychopharmacology. – 1999. – 141, N 2, P. 213-219.
172. Laslop A., Tschernitz C. Effects of nerve growth factor on the biosynthesis of chromogranin A and B, secretogranin II and carboxypeptidase H in rat PC12 cells // Neuroscience. -1992. – 49, N 2. – P. 443-450.
173. Levin Y., Skidgel R., Erdos E. Isolation and characterization of the subunits of human plasma carboxypeptidase N (kininase I) // Proc. Natl. Acad. Sci. USA. – 1982. – 79. – P. 4618-4622.
174. Li Z.G., Danis V.A., Brooks P.M. Effect of gonadal steroids on the production of IL 1 and IL 6 by blood mononuclear cells in vitro // Clin. Experim. Rheumatol. – 1993. – 11, N 2. – P. 157-162.
175. Liu X., Wang C.A., Chen Y.Z. Nongenomic effect of glucocorticoid on the release of arginine vasopressin from hypothalamic slices in rats // Neuroendocrinology. – 1995. – 62, N 6. – P. 628-633.
176. Loh Y.P., Parish D.C., Tuteja R. Purification and charasterization of a paired basic residue-specific pro-opiomelanocortin converting enzyme from bovine pituitary intermediate lobe secretory vesicles // J. Biol. Chem. – 1985. – 260, N 12. – P. 7194-7205.
177. Loh Y.P., Birch N.P., Castro M.G. Pro-opiomelanocortin and pro-vasopressin converting enzyme in pituitary secretory vesicles // Biochimie. – 1988. – 70, N 1. – P. 11-16.
178. Loh Y.P., Snell C.R., Cool D.R. Receptor mediated targeting of hormones to secretory granules, role of carboxypeptidase E // Trends Endocrinol. Met. – 1997. – 8, N 4, P. 130-137.
179. Lowry O.H., Rosebrought N.J., Farr A.G., Randall R.J. Protein measurement with Folin phenol reagent // J. Biol. Chem. – 1951. – 193, N 1. – P. 265-275.
180. Lynch D.R., Braas K.M., Hutton J.C., Snyder S.H. Carboxypeptidase E (CPE) immunocytochemical localization in the rat central nervous system and pituitary gland // J. Neurosci. – 1990. – 10. – N 5. – P. 1592-1599.
181. Lynch D.R., Venable J.C., Snyder S.H. Enkephalin convertase in the heart: similar disposition to atrial natriuretic factor // Endocrinology. – 1988. – 122, N 6. – P. 2683-2691.
182. Lynch D.R., Venable J.C., Strittmatter S.M., Snyder S.H. Enkephalin convertase: charasterization and localization using [3H]guanidinoethylmercaptosuccinic acid // Biochimie. – 1988. – 70, N 1. – P. 57-64.
183. MacCumber M.W., Snyder S.H., Ross C.A. Carboxypeptidase E (enkephalin convertase): mRNA distribution in rat brain by in situ hybridization // J. Neurosci. – 1990. – 10, N 8. – P. 2850-2860.
184. Mackin R.B., Spiess J., Goodman R.H, Noe B.D. Primary structure and tissue distribution of anglerfish carboxypeptidase H. // Mol. Cell Endocrinol. – 1991. – 78, N 3. – P. 171-178.
185. Mackin, R.B., Noe, B.D. Charasterization of an islet carboxypeptidase B involved in prohormone processing // Endocrinology. – 1987. – 120, N 2. – P. 457-468.
186. Mains R.E., Eipper B.A. Secretion and regulation of two biosyntetic enzyme activities, peptidyl-glycine a-amidating monooxygenase and a carboxypeptidase, by mouse pituitary corticotropic tumor cells // Endocrinology. – 1984. – 115, N 5. – P. 1683-1690.
187. Manser E., Fernandez D., Loo L., Goh P.Y., Monfries C., Hall C., Lim L. Human carboxypeptidase E., Isolation and characterization of the cDNA, sequence conservation, expression and processing in vitro // Biochem. J. 1990. – 267, N 2. – P. 517-525.
188. Marks N., Berg N., Benuck M., Lo E. –S., Novachenko H., Seyfried C. Prodynorphin processing by rat CNS fractions and purified enzyme: formation of dynorphin A 1-8 by sulfhydryl activated carboxypeptidase and peptidyl dipeptidase // Neurochem. Intern. – 1987. – 10, N 4. – P. 413-422.
189. Marks N., Grynbaum A., Benuck M. On the sequential cleavage of myelin basic protein by cathepsin A and D // J. Neurochem. – 1976. – 27. – P. 765-768.
190. Martinez F., Tesarik J., Martin C.M., Soler A., Mendoza C. Stimulation of tyrosine phosphorylation by progesterone and its 11-oh derivatives - dissection of a Ca2+-dependent and a Ca2+-independent mechanism // Biochem. Biophis. Res. Comm. – 1999. – 255, N 1. – P. 23-27.
191. Matsumoto H., Mori T. Changes in cystine aminopeptidase (oxytocinase) activity in mouse serum, placenta, uterus and liver duringpregnancy or after steroid hormone treatments // Zool. Sci. – 1998. – 15, N 1. – P. 111-115.
192. Mazer N.A. Mimicking the circadian pattern of testosterone and metabolite levels with an enhanced transdermal delivery system // Gurney, Junjinger, Peppas, eds. Pulsatile Drug Delivery: Current Applications and Future Trends. Stuttgart: Wiss. Veri. –Ges. – 1993. – P. 73-97.
193. Mcabee M.D., Doncarlos L.L. Ontogeny of region specific sex differences in androgen receptor messenger ribonucleic acid expression in the rat forebrain // Endocrinology. – 1998. – 139, N 4. – P. 1738-1745.
194. McDonald J.K., Schwabe C. Intracellularexopeptidase // Proteinases in mammalian cells and tissues / Barrett A.J. (ed.). Amsterdam: Elsevier/North Holland Biomedical Press, 1977. – p. 311-391.
195. McKay T.Y., Phelan A.W., Plummer T.H.Jr. Comparative studies on human carboxypeptidases B and N // Arch. Biochem. Biophys. –1979. – 197. – P. 487-492.
196. McKay T.Y., Plummer T.H.Jr. By product-analogues for bovine carboxypeptidase B // Biochemistry. – 1978. – 17. – P. 401-405.
197. McMillian M.K., Hudson P.M., Lee D.Y., Thai L., Hung G.H., Hong J.S. Developmental changes in rat adrenal enkephalin precursor: peptide ratio // Brain Res. Dev. Brain. Res. – 1993. – 71, N 1. – P. 75-80.
198. Melcangi R.C., Froelichsthal P., Martini L., Vescovi A.L. Steroid metabolizing enzymes in pluripotential progenitor central nervous system cells effect of differentiation and maturation // Neuroscience. – 1996. – 72, N 2. – P. 467-475.
199. Melcangi R.C., Maggi R., Martini L. Testosterone and progesterone metabolism in the human neuroblastoma cell-line SH-SY5Y // J. Steroid Biochem.Mol. Biol. – 1993. – 46, N 6. – P. 811—818.
200. Melcangi R.C., Magnaghi V., Cavarretta I., Riva M.A., Martini L. Corticosteroid effects on gene expression of myelin basic protein in oligodendrocytes and of glial fibrillary acidic protein in type 1 astrocytes // J. Neuroendocrinol. – 1997. – 9, N 10. – P. 729-733.
201. Melcangi R.C., Poletti A., Cavarretta I., Celotti F., Colciago A., Magnaghi V., Motta M., Negricesi P., Martini L. The 5 alpha reductase in the central nervous system expression and modes of control // J.Steroid Biochem.Mol. Biol. – 1998. – 65, N 1 6. – P. 295-299.
202. Melrose P., Gross L. Steroid effects on the secretory modalities of gonadotropin-releasing hormone release // Endocrinology. 1987. – 121, N 1. – P. 190—199.
203. Meunier J.C. The opioid peptides and their receptors // Biochem. – 1986. – 68, N 10-11. – P. 1153-1158.
204. Miller L., Hunt J.S. Sex steroid hormones and macrophage function // Life Sciences. – 1996. – 59, N 1. – P. 1-14.
205. Misao R., Itoh N., Mori H., Fujimoto J., Tamaya T. Sex hormone binding globulin mRNA levels in human uterine endometrium // Europ. J. Endocrinol. – 1994. – 131, N 6. – P. 623-629.
206. Mitra A., Song L.X., Fricker L.D. The C-terminal region of carboxypeptidase E is involved in membrane-binding and intracellular routing in AtT-20 cells // J. Biol. Chem. – 1994. – 269, N 31. – P. 19876-19881.
207. Morley J.E. Neuropipdes, behavior and aging // J. Amer. Geriatr. Soc. – 1986. – 34, N 1. – P. 52-62.
208. Moussaoui S., Duval P., Lenoir V., Garret C., Kerdelhue B . CGRP in the trigeminal nucleus, spinal cord and hypothalamus – effect of gonadal steroids // Neuropeptides. – 1996. – 30, N 6. – P. 546-550.
209. Nagae A., Deddish P.A., Becker R.P., Anderson C.H., Abe M., Tan F., Skidgel R.A., Erdos E.G. Carboxypeptidase M in brain and peripheral nerves // J. Neurochem. – 1992. – 59, N 6. – P. 2201-2212.
210. Naggert J.K., Fricker L.D., Varlamov O., Nishina P.M., Rouille Y., Steiner D.F., Carroll R.J., Paigen B.J., Leiter E.H. Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity // Nature Genetics. – 1995. – 10, N 2. – P. 135-42.
211. Nalamachu S.R., Song L.X., Fricker L.D. Regulation of carboxypeptidase E – effect of Ca2+ on enzyme-activity and stability // J. Biol. Chem. – 1994. – 269, N 15. – P. 11192-11195.
212. Neurath H. Carboxypeptidases A and B // Enzymes. – New York, London: Acad Press, 1960. – N 4. – P. 11-36.
213. Nevalainen M.T., Valve E.M., Ahonen T., Yagi A., Paranko J., Harkonen P.L. Androgen dependent expression of prolactin in rat prostate epithelium in vivo and in organ culture // FASEB Journal. – 1997. – 11, N 14. – P. 1297-1307.
214. Nitray J., Sirotkin A., Poltarsky J. Progesterone and testosterone production in granulosa cells of sow ovaries after invitro nonapeptide hormone administration // Veterinarni Medicina. – 1992. – 37, N 7. – P. 371-377.
215. Norenberg U., Richter D. Processing of the oxytocin precursor: isolation of an exopeptidase from neurosecretory granules of bovine pituitaries // Biochem. Biophys. Res. Commun. – 1988. – 156, N 2. – P. 898-904.
216. Normant E., Loh Y.P. Carboxypeptidase E acts as a sorting receptor for routing proinsulin and proenkephalin but not chromogranin A to the regulated secretory pathway // FASEB Journal. – 1997. – 11, N 9, P. 431-431.
217. Normant E., Loh Y.P. Depletion of Carboxypeptidase E, a regulated secretory pathway sorting receptor, causes misrouting and constitutive secretion of proinsulin and proenkephalin, but not chromogranin A // Endocrinology. – 1998. – 139, N 4, P. 2137-2145
218. Nwe K.H.H., Morat P.B., Khalid B.A.K. Opposite effects of sex steroids on 11 beta hydroxysteroid dehydrogenase activity in the normal and adrenalectomized rat testis // Gen. Pharmacol. – 1997. – 28, N 5. – P. 661-664.
219. Olson G.A., Olson R.D., Kastin A.J. Endogenous opiates: 1985 // Peptides. – 1986. – 7, N 5. – P. 907-933.
220. Ortego J., Escribano J., Crabb J., Coca Prados M. Identification of a neuropeptide and neuropeptide processing enzymes in aqueous humor confers neuroendocrine features to the human ocular ciliary epithelium // J. Neurochem. – 1996. – 66, N 2. – P. 787-796.
221. Oyarce A.M., Hand T.A., Mains R.E., Eipper B.A. Dopaminergic regulation of secretory granule associated proteins in rat intermediate pituitary // J. Neurochem. – 1996. – 67, N 1. – P. 229-241.
222. Parkinson D. Carboxypeptidase H in bovine pituitary gland: soluble forms are not processed at the C-terminus // Mol. Cell. Endocrinol. – 1992. – 86, N 3. – P. 221-233.
223. Parkinson D. Two soluble forms of bovine carboxypeptidase H have different NH2-terminal sequences // J. Biol. Chem. – 1990. – 265, N 28. – P. 17101-17105.
224. Pekary A.E., Lukaski H.C., Mena I., Smith S.M., Bhasin S., Hershman J.M. Testosterone increases TRH biosynthesis in epididymis but not heart of zinc deficient rats // Peptides. – 1993. – 14, N 2. – P. 315-324.
225. Perloff M.D., Kream RM., Beinfeld M.C. Reduced levels of substance P in the brains of Cpe(Fat)/Cpe(Fat) Mice // Peptides. – 1998. – 19, N 6, P. 1115-1117.
226. Pineiro V., Casabiell X., Peino R., Lage M., Camina J.P., Menendez C., Baltar J., Dieguez C., Casanueva F.F. Dihydrotestosterone, stanozolol, androstenedione and dehydroepiandrosterone-sulfate inhibit leptin secretion in female but not in male samples of omental adipose tissue in vitro - lack of effect of testosterone // J. Endocrinology. –1999. – 160, N 3. – P. 425-432.
227. Plummer T.H., Hurwitz M.J. Human plasma carboxypeptidase N. Isolation and characterization // J. Biol. Chem. – 1978. – 253. –P. 3907-3912.
228. Pointis G, Latreille M.T, Richard M.O, D'Athis P., Cedard L. Effect of natural progesterone treatment during pregnancy on fetal testosterone and sexual behavior of the male offspring in the mouse // Dev. Pharmacol. Ther. – 1987. –10, N 5. – P. 385-392.
229. Porcelli G., Raffaelli R., Sacchi A., Volpe A.R., Miani C. Localization and characterization of human salivary kininases // Agents Actions Suppl. – 1992. – 38, N 1. – P. 401-406.
230. Pshezhetsky A.V., Potier M. Direct affinity purification and supramolecular organization of human lysosomal cathepsin A // Arch. Biochem. Biophys. – 1994. – 313, N 1. – P. 64-70.
231. Richer J.K., Lange C.A., Wierman A.M., Brooks K.M., Tung L., Takimoto G.S., Horwitz K.B. Progesterone Receptor Variants Found in Breast Cells Repress Transcription by Wild Type Receptors // Breast Canc. Res. Treat. – 1998. – 48, N 3. – P. 231-241.
232. Rodriguez C., Brayton K.A., Brownstein M., Dixon J.E. Rat preprocarboxypeptidase H. Cloning, characterization, and sequence of the cDNA and regulation of the mRNA by corticotropin releasing factor // J. Biol. Chem. – 1989. – 264, N 10. – P. 5988-5995.
233. Roselli C.E., Klosterman S.A. Sexual differentiation of aromatase activity in the rat brain effects of perinatal steroid exposure // Endocrinology. – 1998. – 139, N 7. – P. 3193-3201.
234. Rossier, J., Barres, E., Hutton, J.C., Ricknell, R.J. Radiometric assay for carboxypeptidase H (EC 3.4.17.10) and other carboxypeptidase B-like enzymes // Anal. Biochem. – 1989. – 178, N 1. – P. 27-31.
235. Rouille Y., Chauvet J., Acher R. Partial conversion of vasopressinyl-Gly-Lys-Arg into pharmacologically active vasopressin through secretory granule carboxypeptidase E and alpha-amidating processing enzymes // Biochem. Int. – 1992. – 26, N 4. – P.739-746.
236. Rovere C., Viale A., Nahon J., Kitabgi P. Impaired processing of brain proneurotensin and promelanin concentrating hormone in obese fat/fat mice // Endocrinology. – 1996. – 137, N 7. – P. 2954-2958.
237. Schlamp C.L., Nickells R.W. Light and dark cause a shift in the spatial expression of a neuropeptide processing enzyme in the rat retina // J. Neurosci. – 1996. – 16, N 7. – P. 2164-2171.
238. Seidah N.G., Chretien M. Proprotein and prohormone convertases of the subtilisin family - recent developments and future perspectives // Trends Endocrinol. Met. – 1992. – 3, N 4. – P. 133-140.
239. Sheikh I.A., Kaplan A.P. Mechanism of digestion of bradykinin and lysylbradykinin (kallidin) in human serum. Role of carboxypeptidase, angiotensin-converting enzyme and determination of final degradation products // Biochem. Pharmacol. – 1989. – 38, N 6. – P. 993-1000.
240. Shen F.S., Loh Y.P. Intracellular Misrouting and Abnormal Secretion of Adrenocorticotropin and Growth Hormone in Cpe (Fat) Mice Associated with a Carboxypeptidase E Mutation // Proc. Nat. Acad. Sci. USA. – 1997. – 94, N 10. – P. 5314-5319.
241. Shinohara T., Sakurada C., Suzuki T., Takeuchi O., Campbell W., Ikeda S., Okada N., Okada H. Pro-carboxypeptidase R cleaves bradykinin following activation // Int. Arch. Allergy Immunol. – 1994. – 103, N 4. – P. 400-404.
242. Silva W.I., Benitez K., Ocasio J., Martinez L., Rosario N. Neuropeptide like immunoreactivities and carboxypeptide H activity associated with bovine brain clathrin coated vesicles // Neuropeptides. –1995. – 28, N 6, P. 341-349.
243. Sirotkin A.V. Involvement of steroid hormones in bovine oocytes maturation invitro // J. Steroid Biochem. Mol. Biol. – 1992. – 41, N 38. – P. 855-858.
244. Sirotkin A.V., Nitray J. Steroid hormones regulate cAMP and cGMP production by porcine granulosa cells in vitro // J. Steroid Biochem. Mol. Biol. – 1993. – 46, N 5. – P. 573-577.
245. Sirotkin A.V., Nitray J., Skokanova A., Politov V.P., Jurcovicova J. Marinchenko G.V. Release of a prolactin like substance by bovine granulosa cells in vitro: effects of ovarian steroids // Annales de Endocrinologie. – 1994. – 55, N 6. – P. 279-282.
246. Skidgel R.A., Bennett C.D., Schilling J.W., Tan F.L., Weerasinghe D.K., Erdos E.G. Amino acid sequence of the N-terminus and selected tryptic peptides of the active subunit of human plasma carboxypeptidase N: comparison with other carboxypeptidases // Biochem. Biophys. Res. Commun // 1988. – 15, N 154 (3). – P. 1323-1329.
247. Skidgel R.A., Davis R.M., Tan F. Human carboxypeptidase M. Purification and characterization of a membrane-bound carboxypeptidase that cleaves peptide hormones // J. Biol. Chem. – 1989. – 264, N 4. – P. 2236-2241.
248. Skidgel R.A., Johnson A.R., Erdos E.G. Hydrolisys of opioid hexapeptides by carboxypeptidase N. Presence of carboxypeptidase in cell membranes // Biochem. Pharmacol. – 1984. – 33, N 21. – P. 3471-3478.